Title of article :
Asymmetric synthesis of 2-substituted cyclic amines
Author/Authors :
Kudale، نويسنده , , Amit A. and Anaspure، نويسنده , , Prasad and Goswami، نويسنده , , Falguni and Voss، نويسنده , , Matthew، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2014
Abstract :
Cyanomethylenetributylphosphorane-mediated ring closure for the asymmetric synthesis of 2-substituted cyclic amines such as azetidines, pyrrolidines and a piperidine is reported. The desired stereochemistry at the 2-position was fixed using (S)-tert-butyl sulfinamide as a chiral auxiliary.
Keywords :
chiral auxiliary , asymmetric synthesis , Cyclic amines , Cyanomethylenetributylphosphorane
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
