Author/Authors :
Taylor، نويسنده , , Andrew J and Bobik، نويسنده , , Alex and Berndt، نويسنده , , Michael C and Kalff، نويسنده , , Victor and Michaelides، نويسنده , , Alexandra and Jennings، نويسنده , , Garry L.R، نويسنده ,
Abstract :
We assessed glycoprotein (GP) IIb/IIIa independent platelet activation in coronary sinus and peripheral blood from patients who underwent angioplasty for acute myocardial infarction and stable angina. Despite complete blockade of the activated GP IIb/IIIa receptor with abciximab in patients with acute myocardial infarction, unsuppressed local GP IIb/IIIa independent activation was associated with a lack of recovery of left ventricular function.