Author/Authors :
Messerli، نويسنده , , Adrian W. and Seshadri، نويسنده , , Niranjan and Pearce، نويسنده , , Gregory L. and Sachar، نويسنده , , Ravish and Hoogwerf، نويسنده , , Byron J. and Sprecher، نويسنده , , Dennis L.، نويسنده ,
Abstract :
We hypothesized that the association of high sensitivity C-reactive protein (CRP) with urinary albumin excretion (UAE) is predominately mediated through its correlation with the metabolic syndrome. Serum CRP and urine albumin:creatinine ratios (ACR) from 720 preventive cardiology patients were analyzed to estimate age- and gender-adjusted relative risk of high CRP and metabolic syndrome for high ACR. These data demonstrate that CRP independently predicts the presence of UAE, a marker of endothelial dysfunction.
