Author/Authors :
Cutlip، نويسنده , , Donald E. and Ricciardi، نويسنده , , Mark J. and Ling، نويسنده , , Frederick S. and Carrozza Jr.، نويسنده , , Joseph P. and Dua، نويسنده , , Vineet and Garringer، نويسنده , , Jason and Giri، نويسنده , , Satyendra and Caputo، نويسنده , , Ronald P.، نويسنده ,
Abstract :
Sixty-one patients with ST elevation acute myocardial infarction were randomized to receive open-label tirofiban in the emergency room before primary angioplasty versus glycoprotein IIb/IIIa inhibitors administered after initial coronary angiography. Early administration of tirofiban before primary angioplasty resulted in nonsignificant improvement in initial coronary flow (Thrombolysis In Myocardial Infarction trial grade 2 or 3 flow, 39% vs 27%, p >0.20). Patients receiving early tirofiban treatment were more likely to achieve complete (>70%) ST-segment resolution at 90 minutes (69% vs 44%, p = 0.07).
