Effectiveness of ezetimibe in clinical practice

We retrospectively evaluated the effect of ezetimibe in a population of patients with hypercholesterolemia referred to a lipid clinic. Ezetimibe decreased low-density lipoprotein cholesterol by 22% in all patients treated with this medication (n = 87). Ezetimibe was also effective in patients treated with this agent alone (−23%, n = 21), with a statin (−23%, n = 28), with a nonstatin (−21%, n = 18), and with both a statin and a nonstatin (−22%, n = 20).