• Title of article

    Role of xanthine oxidase in conduit artery endothelial dysfunction in cigarette smokers

  • Author/Authors

    Guthikonda، نويسنده , , Sashi and Woods، نويسنده , , Kenneth and Sinkey، نويسنده , , Christine A. and Haynes، نويسنده , , William G.، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2004
  • Pages
    5
  • From page
    664
  • To page
    668
  • Abstract
    Xanthine oxidase contributes to oxidant stress and has been proposed as a risk factor for endothelial dysfunction. We studied the role of xanthine oxidase in conduit artery endothelial dysfunction in 12 smokers and 12 controls. Conduit artery vasodilation was impaired in smokers (4.3%) compared with controls (7.9%) (p = 0.006) and improved with xanthine oxidase inhibition in smokers (9.2%, p <0.001).
  • Journal title
    American Journal of Cardiology
  • Serial Year
    2004
  • Journal title
    American Journal of Cardiology
  • Record number

    1897174