Author/Authors :
Schussler، نويسنده , , Jeffrey M and Lander، نويسنده , , Stuart R and Wissinger، نويسنده , , Laurie A and Anwar، نويسنده , , Azam and Donsky، نويسنده , , Michael S and Johnson، نويسنده , , Kenneth B and Vallabhan، نويسنده , , Ravi C and Wischmeyer، نويسنده , , Jason B، نويسنده ,
Abstract :
Bivalirudin is being used more frequently as an anticoagulant in the cardiac catheterization laboratory. Newer devices, used to measure activated clotting time (ACT), have not been thoroughly tested for use with bivalirudin. One such device, the i-STAT ACT, measures the generation of activated thrombin to determine the level of anticoagulation. Our study demonstrated a high level of agreement between the i-STAT ACT and the Hemochron ACT in patients anticoagulated with bivalirudin. In addition, the i-STAT was shown to have an extremely high degree of reproducibility.