Author/Authors :
Kawamoto، نويسنده , , Riichirou and Hatakeyama، نويسنده , , Kinta and Imamura، نويسنده , , Takuroh and Ishikawa، نويسنده , , Tetsunori and Date، نويسنده , , Haruhiko and Shibata، نويسنده , , Yoshisato and Takenaga، نويسنده , , Makoto and Asada، نويسنده , , Yujiro and Eto، نويسنده , , Tanenao، نويسنده ,
Abstract :
To determine whether the inflammatory response is equally involved in the pathogenesis of restenosis after coronary stenting and directional coronary atherectomy, we assessed restenotic lesions with immunohistochemical methods. Levels of C-reactive protein and macrophages were greater in patients with in-stent restenosis than in those with restenosis after directional coronary atherectomy. This suggests that the inflammatory response is more involved in the pathogenesis of in-stent restenosis than in restenosis after directional coronary atherectomy.