Author/Authors :
Qin، نويسنده , , Jian Xin and Shiota، نويسنده , , Takahiro and Asher، نويسنده , , Craig R. and Smedira، نويسنده , , Nicholas G. and Shin، نويسنده , , Joon-Han and Agler، نويسنده , , Deborah A. and Nash، نويسنده , , Patrick J. and Greenberg، نويسنده , , Neil L. and Lever، نويسنده , , Harry M. and Lytle، نويسنده , , Bruce W. and Thomas، نويسنده , , James D.، نويسنده ,
Abstract :
Real-time 3-dimensional echocardiography was performed in 10 patients with obstructive hypertrophic cardiomyopathy (HC) before and after myectomy and in 6 controls. The exact location of systolic anterior motion of the mitral leaflet was shown in all patients with HC with a predominant involvement of the medial portion in 4 patients and the middle portion in 6 patients. The smallest area of the left ventricular outflow tract was significantly smaller in patients with HC than in controls (1.4 ± 0.7 vs 5.1 ± 1.2 cm2, p <0.01), significantly increased after myectomy (4.8 ± 1.8 cm2, p <0.01) and was associated with a reduction of the pressure gradient at rest from 63 ± 41 to 15 ± 5 mm Hg (p <0.01).