Author/Authors :
Merino، نويسنده , , Alvaro and Gayل، نويسنده , , Antonio and Segura، نويسنده , , Juan Ignacio Perez-Calvo، نويسنده , , Javier and Imيzcoz، نويسنده , , Cristina and Berenguel، نويسنده , , Alejandro and Alegrيa، نويسنده , , Eduardo، نويسنده ,
Abstract :
C-reactive protein (CRP), interleukin-6 (IL-6), and the −174 GC IL-6 gene polymorphism were analyzed after coronary angioplasty in 50 patients, 25 of whom were treated with the glycoprotein IIb/IIIa platelet receptor inhibitor eptifibatide for 24 hours. It was found that glycoprotein IIb/IIIa inhibition significantly blocked postangioplasty CRP increases in all patients but blocked IL-6 increases only in patients carrying the −174 GG genotype.
