Author/Authors :
Hyodo، نويسنده , , Eiichi and Hozumi، نويسنده , , Takeshi and Takemoto، نويسنده , , Yasuhiko and Fujimoto، نويسنده , , Kohei and Watanabe، نويسنده , , Hiroyuki and Muro، نويسنده , , Takashi and Shimada، نويسنده , , Kenei and Akioka، نويسنده , , Kaname and Yoshiyama، نويسنده , , Minoru and Takeuchi، نويسنده , , Kazuhide and Yoshikawa، نويسنده , , Junichi، نويسنده ,
Abstract :
This study examined the effect of azithromycin therapy on the coronary microcirculation using measurement of coronary flow velocity reserve (CFVR) by transthoracic Doppler echocardiography in 35 patients with coronary artery disease. CFVR increased significantly after azithromycin therapy (3.0 ± 0.7 vs 3.5 ± 0.7, p <0.001). The changes in CFVR were negatively correlated with changes in high-sensitivity C-reactive protein levels in patients receiving azithromycin.