Author/Authors :
da Costa، نويسنده , , L.يlian Soares and de Oliveira، نويسنده , , Monica Amorim and Rubim، نويسنده , , Valéria Siqueira Martins and Wajngarten، نويسنده , , Maurيcio and Aldrighi، نويسنده , , José Mendes and Rosano، نويسنده , , Giuseppe M. and Neto، نويسنده , , Cantidio Drumond and Gebara، نويسنده , , Otavio Celso Eluf، نويسنده ,
Abstract :
The administration of oral raloxifene in 30 postmenopausal hypertensive women was evaluated to demonstrate its effect on arterial stiffness. Casual and ambulatory blood pressure (BP) and pulse-wave velocity (PWV) data were obtained before and after patients received raloxifene, estrogen–progestin replacement therapy, or placebo in a randomized crossover study. It was shown that the 2 therapies decreased BP and carotid–femoral PWV, and the effect of raloxifene on vascular compliance was independent of the effects on BP.
