Author/Authors :
Mintz، نويسنده , , Gary S. and Hong، نويسنده , , Myeong-Ki and Raizner، نويسنده , , Albert E. and Lee، نويسنده , , Cheol Whan and Kim، نويسنده , , Jae-Joong and Escolar، نويسنده , , Esteban and Fearnot، نويسنده , , Neal E. and Park، نويسنده , , Seong-Wook and Park، نويسنده , , Seung-Jung and Weissman، نويسنده , , Neil J.، نويسنده ,
Abstract :
Using data from the ASian Paclitaxel-Eluting Stent Clinical Trial, a 3-center, randomized, placebo-controlled trial of nonpolymeric paclitaxel-coated stents with a single center, 81-patient intravascular ultrasound (IVUS) substudy, the length of a stent that was free of IVUS-detectable intimal hyperplasia measured 3.2 ± 4.8 mm in placebo stents, 6.1 ± 5.6 mm in low-dose stents, and 8.7 ± 6.1 mm in high-dose stents (p = 0.0029). IVUS percent neointima volume obstruction correlated with the length of this IVUS neointima-free segment (r = 0.785, p <0.0001); angiographic late lumen loss and follow-up diameter stenosis also correlated with the IVUS neointima-free length of the stents (r = 0.670, p <0.0001 and r = 0.679, p <0.0001, respectively.