Author/Authors :
von Haehling، نويسنده , , Stephan and Genth-Zotz، نويسنده , , Sabine and Bolger، نويسنده , , Aidan P. and Kalra، نويسنده , , Paul R. and Kemp، نويسنده , , Michael and Adcock، نويسنده , , Ian M. and Poole-Wilson، نويسنده , , Philip A. and Dietz، نويسنده , , Rainer and Anker، نويسنده , , Stefan D.، نويسنده ,
Abstract :
Increased levels of tumor necrosis factor-α (TNF-α) correlate with poor prognoses in chronic heart failure (CHF). This study demonstrated that noradrenaline and isoproterenol inhibit TNF-α production in patients with CHF in ex vivo whole blood in a dose-dependent fashion. The β-blocker bisoprolol abolishes this effect.
