Author/Authors :
Velagaleti، نويسنده , , Raghava S. and Pencina، نويسنده , , Michael J. and Vasan، نويسنده , , Ramachandran S. and Benjamin، نويسنده , , Emelia J. and Massaro، نويسنده , , Joseph M. and Pencina، نويسنده , , Karol and Levy، نويسنده , , Daniel، نويسنده ,
Abstract :
Although previous investigations reported on the associations of lipid concentrations with left ventricular remodeling in specific subpopulations, few data exist on these associations in a community-based sample of subjects without cardiovascular disease. In this study, 3,554 Framingham Heart Study participants (mean age 47 years, 53% women) without preexisting clinical cardiovascular disease were examined, and no meaningful associations of high-density lipoprotein cholesterol or non–high-density lipoprotein cholesterol with echocardiographic indexes of left ventricular structure were observed. In conclusion, these data do not support an independent association between lipid concentrations and left ventricular structure.