Author/Authors :
Koulouris، نويسنده , , Spyridon and Symeonides، نويسنده , , Phivos and Triantafyllou، نويسنده , , Konstantinos and Ioannidis، نويسنده , , Georgios and Karabinos، نويسنده , , Ilias and Katostaras، نويسنده , , Theofanis and El-Ali، نويسنده , , Mahmud and Theodoridis، نويسنده , , Theodoros and Vratsista، نويسنده , , Ekaterini and Thalassinos، نويسنده , , Nikolaos and Kokkinou، نويسنده ,
Abstract :
The effect of ramipril (an angiotensin [AT]-converting enzyme inhibitor), telmisartan (an AT-II type 1 receptor blocker), or their combination on inflammation and lipid peroxidation was assessed in 37 patients with type 2 diabetes who were free of coronary artery disease. All regimens were associated with a significant reduction of C-reactive protein and oxidized low-density lipoprotein cholesterol serum levels (p <0.001). These results further enlighten the mechanisms underlying the cardiovascular beneficial effect of renin-AT system inhibition.
