Author/Authors :
Kinjo، نويسنده , , Kunihiro and Sato، نويسنده , , Hiroshi and Sakata، نويسنده , , Yasuhiko and Nakatani، نويسنده , , Daisaku and Mizuno، نويسنده , , Hiroya and Shimizu، نويسنده , , Masahiko and Nishino، نويسنده , , Masami and Ito، نويسنده , , Hiroshi and Tanouchi، نويسنده , , Jun and Nanto، نويسنده , , Shinsuke and Hori، نويسنده , , Masatsugu، نويسنده ,
Abstract :
We evaluated the interaction between inflammation and survival benefit from statin therapy in patients who had acute myocardial infarction. Although 1-year mortality did not differ between patients who used statin therapy and those who did not, among patients who had C-reactive protein (CRP) concentrations in the lower 2 tertiles (<2.9 mg/L), 1-year mortality was higher in patients who used statin therapy than in those who did not within the highest CRP-defined tertile (≥2.9 mg/L). Statin therapy significantly decreased the hazard ratio for 1-year mortality in patients who had high CRP levels to approximately the hazard present for patients who had low CRP levels and did not receive statin therapy.
