Author/Authors :
Kaneda، نويسنده , , Hideaki and Koizumi، نويسنده , , Tomomi and Ako، نويسنده , , Junya and Terashima، نويسنده , , Mitsuyasu and Morino، نويسنده , , Yoshihiro and Honda، نويسنده , , Yasuhiro and Yock، نويسنده , , Paul G. and Leon، نويسنده , , Martin B. and Moses، نويسنده , , Jeffrey W. and Fitzgerald، نويسنده , , Peter J.، نويسنده ,
Abstract :
The effect of lesion characteristics on neointimal hyperplasia after sirolimus-eluting stent implantation was examined in 45 patients who underwent successful preinterventional intravascular ultrasound. There were no differences in neointimal hyperplasia between the moderate/severe calcified lesion group (calcium arc >120°) and the non/mild calcified lesion group or between the positive vessel remodeling group (external elastic membrane area at the minimal lumen area site larger than that at the proximal reference site) and negative vessel remodeling group. No correlation between preinterventional plaque burden and neointimal hyperplasia was found. In patients who have coronary artery disease, sirolimus-eluting stents continue to demonstrate striking suppression of neointimal proliferation, irrespective of lesion characteristics previously associated with greater restenotic risk.
