Author/Authors :
Kaneda، نويسنده , , Hideaki and Ako، نويسنده , , Junya and Honda، نويسنده , , Yasuhiro and Terashima، نويسنده , , Mitsuyasu and Morino، نويسنده , , Yoshihiro and Yock، نويسنده , , Paul G. and Popma، نويسنده , , Jeffrey J. and Leon، نويسنده , , Martin B. and Moses، نويسنده , , Jeffrey W. and Fitzgerald، نويسنده , , Peter J.، نويسنده ,
Abstract :
To assess whether asymmetric stent expansion affects suppression of neointimal hyperplasia after sirolimus-eluting stent implantation, 64 patients in the SIRolImUS-coated Bx Velocity stent trial who underwent single 18-mm stent implantation and 3-dimensional intravascular ultrasonography at 8-month follow-up were enrolled. To assess the longitudinal stent asymmetric expansion, 2 cross sections with a maximal/minimal stent area were chosen in each patient. To assess for tomographic stent asymmetric expansion, stent eccentricity was determined by dividing the minimum stent diameter by the maximum stent diameter. At the 2 cross sections with a maximal/minimal stent area, a sirolimus-eluting stent reduced neointimal hyperplasia significantly with no interaction between the treatment and stent areas. A sirolimus-eluting stent also significantly reduced neointimal hyperplasia in the concentric and eccentric stent groups.
