Author/Authors :
Osugi، نويسنده , , Naohiro and Suzuki، نويسنده , , Susumu and Ishii، نويسنده , , Hideki and Yasuda، نويسنده , , Yoshinari and Shibata، نويسنده , , Yohei and Tatami، نويسنده , , Yosuke and Ota، نويسنده , , Tomoyuki and Kawamura، نويسنده , , Yoshihiro and Okumura، نويسنده , , Satoshi and Tanaka، نويسنده , , Akihito and Inoue، نويسنده , , Yosuke and Matsuo، نويسنده , , Seiichi and Murohara، نويسنده , , Toyoaki، نويسنده ,
Abstract :
Albuminuria has traditionally been associated with an elevated risk of cardiovascular events. However, few studies have examined the potential relation between albuminuria and periprocedural risk in percutaneous coronary intervention (PCI). The aim of this study was to evaluate the impact of albuminuria on the incidence of periprocedural myocardial injury (PMI) in patients who underwent PCI. The study included 252 consecutive patients who underwent PCI. The incidence of PMI was significantly higher in patients with albuminuria than in those with normoalbuminuria (31.9% vs 43.3%, respectively, p = 0.014). Even after adjustment for confounders, the presence of albuminuria predicted PMI (odds ratio 2.07, 95% confidence interval 1.08 to 3.97, p = 0.029). Furthermore, patients with albuminuria and preserved estimated glomerular filtration rate had a 4.2-fold higher risk for PMI than did patients with normoalbuminuria and preserved estimated glomerular filtration rate. In conclusion, albuminuria was a strong predictor of PMI in patients who underwent PCI.