Author/Authors :
Araki، نويسنده , , Sumiko and Nakai، نويسنده , , Tonau and Hizume، نويسنده , , Kohji and Takeyasu، نويسنده , , Kunio and Yoshikawa، نويسنده , , Kenichi، نويسنده ,
Abstract :
It is generally accepted that linear polymers are larger, such as with regard to the end-to-end distance and gyration radius, than the corresponding circular polymers. We measured the Brownian motion of individual linear and circular 106-kbp DNA molecules using fluorescence microscopy. Unexpectedly, the hydrodynamic radius of linear DNA was markedly smaller than that of circular DNA.