Title of article
Conjugation of catecholamines on magnetic nanoparticles coated with sulfonated chitosan
Author/Authors
Qiao، نويسنده , , Ting and Wu، نويسنده , , Yihang and Jin، نويسنده , , Jing and Gao، نويسنده , , Wei and Xie، نويسنده , , Qiaozhen and Wang، نويسنده , , Shuang and Zhang، نويسنده , , Yu and Deng، نويسنده , , Huihua، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2011
Pages
6
From page
169
To page
174
Abstract
We synthesized a novel magnetic nanoparticle coated with sulfonated complex (HSO3-CS-DMSA) of meso-2, 3-dimercaptosuccinic acid (DMSA) and chitosan (CS) to improve conjugation of catecholamines (CAs) on nanoparticles. HSO3-CS-DMSA@MNPs exhibited the highest CAs’ conjugation efficiency among three types of magnetic nanoparticles. CAs’ conjugation efficiency was increased in order of MNPs, DMSA@MNPs and HSO3-CS-DMSA@MNPs. CAs’ conjugation efficiency at pH 7 depended on zeta potential of magnetic nanoparticles and catecholamines were partly desorbed after being washed with acidic solutions. These results showed that the electrostatic interaction between the negatively charged nanoparticles and positively charged amino groups of catecholamines might play an important role in CAs’ conjugation on magnetic nanoparticles.
Keywords
Magnetic nanoparticle , Sulfonation , catecholamines , Chitosan , Conjugation
Journal title
Colloids and Surfaces A Physicochemical and Engineering Aspects
Serial Year
2011
Journal title
Colloids and Surfaces A Physicochemical and Engineering Aspects
Record number
1939906
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