Large vesicles of ethylenediaminediacetic in ethanol due to hydrogen bonding

Bola surfactant ethylenediaminediacetic (EDDA) was successfully synthesized with using a novel approach. For composites obtained through the supramolecular organization in the ethanol solution, transition behavior of vesicle morphology such as worm-like, petal-like, clustered worm-like, saccules and spherical, was captured by transmission electron microscopy (TEM). In vesicles mentioned above well-defined large spherical aggregations, some of which were solid vesicles, some hollow ones and some multilamellar ones about 1.0–1.5 μm, were evidenced by fluorescence microscope. Furthermore, the morphologies and properties of the vesicles were elucidated by means of Fourier transform infrared spectroscopy (FTIR), laser particle size analyzer, geometry simulation of supramolecular architectures and fluorescence spectrophotometer. On the basis of these analyses, the main driving force of large vesicles was considered to be the strong hydrogen bonding interaction among the exposed hydrophilic part of the EDDA surfactant. During the whole process, the ethanol solution played a very important synergistic role in forming self-assembly aggregate in this system.