Solid state structural study on recognition of aromatic dicarboxylic acids by substituted amino-pyrimidines and its supramolecular network

A series of co-crystals containing substituted 2-aminopyrimidines (2AP) with different dicarboxylic acids have been synthesized and their interactive modes have been characterized by single crystal X-ray studies. For this purpose three complexes containing 2-amino-4,6-dimethylpyrimidine and terephthalic acid (complex 1), 2-amino-4-methyl-6-phenylpyrimidine and isophthalic acid (complex 2), 2-amino-4,6-diphenylpyrimidine and terephthalic acid (complex 3) have been synthesized. Substituents of the 2AP ring have been changed carefully from dimethyl, methyl–phenyl to diphenyl in increasing order of their size to study the change in their crystal engineering and overall supramolecular architecture.