Monitoring multi-class pesticide residues in fresh grape by hollow fibre sorptive extraction combined with gas chromatography–mass spectrometry

A fast and sensitive multi-residue analysis method is reported for simultaneous determination of 25 pesticides of chemical classes which are spiked into fresh grape. The sample pretreatment method involves extraction and clean-up in one step with SiO2 hollow fibre from 1.0 mL fresh grape slurry to minimise the matrix effects, and determination by gas chromatography–mass spectrometry with selective ion monitoring mode. The validation of the optimised method in terms of linearity, precision, recovery and repeatability showed that the proposed procedure is sensitive (the limits of detection were in the range of 0.0009–0.0084 μg mL−1 for 25 pesticides), precise and repeatable (average recoveries were between 61% and 108% with relative standard deviations from 4.0% to 12.4 %). The proposed method was also applied to the analysis of these groups of pesticides in fresh grape sample purchased from the local markets of Lanzhou (China), while no residues of the selected pesticides were detected in the sample.