Solubility of disodium 5′-guanylate heptahydrate in aqueous methanol mixtures

The solubility of disodium 5′-guanylate heptahydrate (5′-GMPNa2) in binary aqueous methanol solvent mixtures with the temperature ranging from 278.15 to 323.15 K was measured by a dynamic method with a laser monitoring observation technique. The solubility data were correlated with the Combined Nearly Ideal Binary Solvent/Redlich–Kister (CNIBS/R–K) model and the modified Jouyban–Acree model, respectively. For the ten groups of data studied, the CNIBS/R–K model was found to provide a more accurate mathematical representation of the experimental data, while the modified Jouyban–Acree model containing provisions for correlating both the solvent composition and temperature.