Title of article
An unexpected isomerization of 1,3-benzothiazine and isoquinoline-condensed β-lactams
Author/Authors
Fodor، نويسنده , , Lajos and Csomَs، نويسنده , , Péter and Fülِp، نويسنده , , Ferenc and Csلmpai، نويسنده , , Antal and Sohلr، نويسنده , , Pلl، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2010
Pages
8
From page
54
To page
61
Abstract
A series of novel aryl-substituted β-lactams condensed with 1,3-benzothiazines, isoquinolines or 1,4-benzothiazepine were obtained by means of the Staudinger reaction and isomerized in the presence of sodium methoxide to the thermodynamically more stable form. The structures of the new molecules were determined by NMR spectroscopy. Theoretical calculations corroborate the experimentally observed structure–reactivity relationships.
Keywords
NMR spectroscopy , DFT analysis , Staudinger reaction , Sulfur nitrogen heterocycles , Cis–trans-?-lactams , Isoquinoline
Journal title
Journal of Molecular Structure
Serial Year
2010
Journal title
Journal of Molecular Structure
Record number
1968299
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