• Title of article

    Synthesis, characterization, antimicrobial and enzymatic activity of 4b,9b-dihydroxy-7,8-dihydro-4bH-indeno[1,2-b]benzofuran-9,10(6H,9bH)-dione

  • Author/Authors

    Mehdi، نويسنده , , Sayed Hasan and Hashim، نويسنده , , Rokiah and Ghalib، نويسنده , , Raza Murad and Fلtima C. Guedes da Silva، نويسنده , , M. and Sulaiman، نويسنده , , Othman and Rahman، نويسنده , , Syed Ziaur and Murugaiyah، نويسنده , , Vikneswaran and Marimuthu، نويسنده , , Mani Maran Ratnam، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2011
  • Pages
    6
  • From page
    318
  • To page
    323
  • Abstract
    The crystal structure of the title compound, 4b,9b-dihydroxy-7,8-dihydro-4bH-indeno[1,2-b]benzofuran-9,10(6H,9bH)-dione has been determined by single crystal X-ray diffraction. It crystallizes in the monoclinic space group P21/c with Z = 4. The FTIR as well as the 1H and 13C NMR spectra of the compound were also recorded and briefly discussed. The compound showed potential antimicrobial activity comparable to that of clinically used antimicrobial agents against selected microorganisms. It has selective and moderate inhibitory activity on butyryl cholinesterase enzyme and could serve as potential lead compound for synthesis of more bioactive derivatives.
  • Keywords
    2-b]benzofuran-9 , 10(6H , Cholinesterase enzymes , 9bH)-dione , crystal structure , NMR spectra , 4b , 9b-Dihydroxy-7 , antimicrobial activity , Inter-molecular hydrogen bonding
  • Journal title
    Journal of Molecular Structure
  • Serial Year
    2011
  • Journal title
    Journal of Molecular Structure
  • Record number

    1969305