Title of article :
Fabrication of cellular polycaprolactone films for cell culture
Author/Authors :
Wang، نويسنده , , Bo and Mao، نويسنده , , Zhengwei and Meng، نويسنده , , Xinan and Tong، نويسنده , , Weijun and Gao، نويسنده , , Changyou، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2010
Abstract :
Hierarchical cellular structures consisting of multilayers of ordered pores were created on a poly-ɛ-caprolactone (PCL) film by introducing a colloidal crystal mask/template in thermomechanical lithography. The surface characteristics were measured by scanning electron microscopy, atomic force microscopy, water contact angle and analyzed by Fourier Transform (FT). The resultant PCL films present a metastable superhydrophobicity. Their water contact angles were initially 150° and then declined with time eventually to 115–120°. In vitro culture of human fibroblasts found that the cells could spread on the cellular PCL surface as normal, but showed higher viability compared with the control cells on a flat substrate.
Keywords :
Biomaterials , fibroblasts , films , Poly-?-caprolactone , Cellular structure
Journal title :
Colloids and Surfaces B Biointerfaces
Journal title :
Colloids and Surfaces B Biointerfaces