Title of article :
Silver nanoparticles impede the biofilm formation by Pseudomonas aeruginosa and Staphylococcus epidermidis
Author/Authors :
Kalishwaralal، نويسنده , , Kalimuthu and BarathManiKanth، نويسنده , , Selvaraj and Pandian، نويسنده , , SureshBabu Ram Kumar and Deepak، نويسنده , , Venkataraman and Gurunathan، نويسنده , , Sangiliyandi، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2010
Pages :
5
From page :
340
To page :
344
Abstract :
Biofilms are ensued due to bacteria that attach to surfaces and aggregate in a hydrated polymeric matrix. Formation of these sessile communities and their inherent resistance to anti-microbial agents are the source of many relentless and chronic bacterial infections. Such biofilms are responsible play a major role in development of ocular related infectious diseases in human namely microbial keratitis. Different approaches have been used for preventing biofilm related infections in health care settings. Many of these methods have their own demerits that include chemical based complications; emergent antibiotic resistant strains, etc. silver nanoparticles are renowned for their influential anti-microbial activity. Hence the present study over the biologically synthesized silver nanoparticles, exhibited a potential anti-biofilm activity that was tested in vitro on biofilms formed by Pseudomonas aeruginosa and Staphylococcus epidermidis during 24-h treatment. Treating these organisms with silver nanoparticles resulted in more than 95% inhibition in biofilm formation. The inhibition was known to be invariable of the species tested. As a result this study demonstrates the futuristic application of silver nanoparticles in treating microbial keratitis based on its potential anti-biofilm activity.
Keywords :
Silver nanoparticles , Anti-biofilm activity , Pseudomonas aeruginosa , Staphylococcus epidermidis , keratitis
Journal title :
Colloids and Surfaces B Biointerfaces
Serial Year :
2010
Journal title :
Colloids and Surfaces B Biointerfaces
Record number :
1971620
Link To Document :
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