Author/Authors :
Lo، نويسنده , , I-Wen and Lin، نويسنده , , Yu-Chi and Liao، نويسنده , , Tzu-Ching and Chen، نويسنده , , Shun-Ying and Lin، نويسنده , , Pi-Han and Chien، نويسنده , , Ching-Te and Chang، نويسنده , , Sui-yuan and Shen، نويسنده , , Ya-Ching، نويسنده ,
Abstract :
Two novel highly oxygenated nortriterpenoids, schisarisanlactones A (1) and B (2), have been isolated from the fruits of Schisandra arisanensis, an endemic plant of Taiwan. Compounds 1 and 2 possess an unprecedented 5/5/7/5/5-fused pentacyclic ring system. The structures of both compounds were determined on the basis of spectroscopic analyses, especially 2D NMR and MS. A plausible biogenetic pathway of 1 was proposed. Schisarisanlactone A (1) showed significant anti-HIV activity.
