Author/Authors :
Luan، نويسنده , , Shifang and Zhao، نويسنده , , Jie and Yang، نويسنده , , Huawei and Shi، نويسنده , , Hengchong and Jin، نويسنده , , Jing and Li، نويسنده , , Xiaomeng and Liu، نويسنده , , Jingchuan and Wang، نويسنده , , Jianwei and Yin، نويسنده , , Jinghua and Stagnaro، نويسنده , , Paola، نويسنده ,
Abstract :
Poly(N-vinyl pyrrolidone) (PNVP) was covalently grafted onto the surface of biomedical poly(styrene-b-(ethylene-co-butylene)-b-styrene) (SEBS) elastomer via a technique of UV-induced graft polymerization combined with plasma pre-treatment. The surface graft polymerization of N-vinyl pyrrolidone (NVP) was confirmed by ATR-FTIR and XPS. Effect of the parameters of graft polymerization, i.e., the initiator concentration, the UV irradiation time and the monomer concentration on the grafting density was investigated. The morphology and the wettability of the PNVP-modified surfaces were characterized by AFM and DSA, respectively. Protein adsorption and platelet adhesion were obviously suppressed after PNVP was grafted onto the SEBS substrates.
Keywords :
N-vinyl pyrrolidone (NVP) , Styrenic block copolymers , Hemocompatibility , UV-induced graft polymerization
