Transition-metal triflate catalyzed unprecedented formation of oxime ketals of tetrahydrofuran via C–H functionalization

Benzaldehyde O-tetrahydrofuran-2-yl oximes were formed through the C–H functionalization from the reaction between benzaldoximes and aqueous tetrahydrofuran catalyzed by water tolerant transition metal triflates (Lewis acids). The formation of oxime ketal has been confirmed from 2D NMR analysis (HMBC and HSQC studies).