Title of article
Synthesis and Pharmacological Evaluation of Some Novel Isatin Derivatives for Antimicrobial Activity
Author/Authors
Bari، S.B. نويسنده 1Department of Pharmaceutical Chemistry, R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur - 425 405 (MS) India , , Agrawal، A.O. نويسنده 1Department of Pharmaceutical Chemistry, R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur - 425 405 (MS) India , , Patil، U.K. نويسنده 2Department of Microbiology, R. C. Patel College of Arts, Science, Commerce, Shirpur - 425 405 (MS) India ,
Issue Information
فصلنامه با شماره پیاپی 0 سال 2008
Pages
5
From page
117
To page
121
Abstract
In the present work, a series of new 5-substituted-3-(4-arylimino)-1-[5-mercapto(1,3,4-oxadiazolyl)]-methyl-indol-2-one (4a-g) have been synthesized by heterocyclization of 5-substituted-3-(4-arylimino)-2-oxo-1-indole acetylhyrazide (3a-g) on treatment with CS2 in ethanolic KOH. The compound 4a was characterized by its elemental analysis, IR, 1HNMR and Mass Spectroscopy. The synthesized compounds (4a-g) were evaluated for in vitro antibacterial activity and antifungal activity against various strains of bacteria and fungi.
Journal title
Journal of Sciences
Serial Year
2008
Journal title
Journal of Sciences
Record number
1983758
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