Comment on “Development of Correlations for Describing Solute Transfer into Acyclic Alcohol Solvents Based on the Abraham Model and Fragment-Specific Equation Coefficients”

Partitioning coefficients into differing acyclic aliphatic alcohols can be described by the linear solvation energy relationship (LSER) equations with 6 fitting parameters to the accuracy of 0.19–0.20 log units. If 6 more fitting parameters are added to account for the slight dependency of the partitioning coefficients on the number of carbon atoms of alcohols, the accuracy improves to 0.15–0.16, comparable to the performance by the 30-parameter model proposed by Sprunger et al. [1].