Title of article
Determination of the solubility, dissolution enthalpy and entropy of Deflazacort in different solvents
Author/Authors
Wang، نويسنده , , Peng and Wang، نويسنده , , Jingkang and Gong، نويسنده , , Junbo and Zhang، نويسنده , , Meijing، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2011
Pages
4
From page
171
To page
174
Abstract
The solubility of Deflazacort in four solvents, acetone, ethyl acetate, ethanol and 2-propanol, was measured at temperatures ranging from 293.15 K to 348.15 K at atmospheric pressure using Laser Monitoring Technique. The solubility data were correlated by the modified Apelblat model. Then the dissolution enthalpy and entropy of Deflazacort were predicted from the solubility data using van’t Hoff equation. In this study, it should be concluded that the viscosity and surface tension of solvents affect the solubility behavior, dissolution enthalpy and entropy of Deflazacort in different solvents.
Keywords
Dissolution entropy , Deflazacort , Dissolution enthalpy , solubility
Journal title
Fluid Phase Equilibria
Serial Year
2011
Journal title
Fluid Phase Equilibria
Record number
1988450
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