Title of article :
A one-pot three-component synthesis of 4,6-diarylpyrimidin-2(1H)-ones (DAPMs) using atomized sodium in THF under sonic condition
Author/Authors :
Pasha، نويسنده , , Mohamed Afzal and Nagashree، نويسنده , , Shrivatsa، نويسنده ,
Abstract :
A simple and an efficient procedure for the synthesis of 4,6-diarylpyrimidin-2(1H)-ones using atomized sodium/THF via a one-pot three-component Biginelli-like cyclocondensation of an aldehyde, a methyl ketone and urea under ultrasonic condition is developed. The method is mild and inexpensive; yields are high and the reactions go to completion within 10–15 min.
Keywords :
Aldehydes , Methyl ketones , 4 , Ultrasound , urea , 6-Diarylpyrimidin-2(1H)-ones (DAPMs) , Atomized sodium
Journal title :
Astroparticle Physics
