Author/Authors :
Rahimi، Vida نويسنده Department of Audiology, School of Rehabilitation, Tehran University of Medical Sciences, Iran , , Farahani، Saeid نويسنده Department of Audiology, School of Rehabilitation, Tehran University of Medical Sciences, Iran , , Jalaie، Shohreh نويسنده , , Saeidpour، Atoosa نويسنده Department of nutrition, School of nutrition and food technology, Shahid Beheshti of Medical Sciences, Tehran, Iran ,
Abstract :
Background and Aim: Omega 3 of essential fatty acids, especially in fish oil form plays an important role in structural, functional, and biological aspects in body. Omega 3 deficiency can have devastating effects on the nervous system and auditory. This study aimed to evaluate auditory threshold in n-3 fatty acid-de?cient rat pups following supplementation of fish oil consumption during the suckling period.
Methods: One sources of omega 3 fatty acid were fed to rat pups of n-3 polyunsaturated fatty acids (PUFA)-deficient dams to compare auditory thresholds in 2, 4, 8, 12 and 16 kHz by auditory brainstem response (ABR) among this group, those with defects with placebo, and control groups. The pupsʹ in supplement group were orally fed 5 mol/g weight of fish oil between the ages of 5 and 21 days.
Results: Results showed significant differences in auditory threshold estimation in 2,4,8,12 and 16 kHz in ABR between study groups. The group with n-3 PUFA deficient with placebo showed a significant increase of the parameters indicated as p < 0.05. Moreover a lower threshold (better) in n-3 PUFA deficient with the fish oil in comparison with n-3 PUFA deficient with placebo (p < 0.05).
Conclusion: The result of study showed effect of omega 3 deficiency on auditory during pregnancy and lactation period and compensation neural auditory threshold in n-3 fatty acid-de?cient rat pups following a supplementation of fish oil consumption during the suckling period.
