Author/Authors :
Ohkubo، نويسنده , , M. and Shigeri، نويسنده , , Y. and Kinumi، نويسنده , , T. and Saito، نويسنده , , N. and Ukibe، نويسنده , , M. and Chen، نويسنده , , Y.E. and Kushino، نويسنده , , A. and Kurokawa، نويسنده , , A. and Sato، نويسنده , , H. and Ichimura، نويسنده , , S.، نويسنده ,
Abstract :
Fragmentation of precursor ions of peptides or proteins is very promising for sequencing with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (TOF-MS). Neutral fragments as well as ions produced by post-source decay (PSD) were measured by a superconducting tunnel junction detector in a linear TOF-MS. It has been demonstrated that the PSD fragments are observable as event bands with different kinetic energies at the same TOF as that of the precursor ions of polystyrene with a nominal mass of 200 kDa and bovine serum albumin of 66.43 kDa.
