Author/Authors :
Zahiri، Samaneh نويسنده Department of Chemistry, Rasht Branch, Islamic Azad University, Rasht, Iran , , Mokhtary، Masoud نويسنده , , Torabi، Mogharab نويسنده Department of Chemistry, Rasht Branch, Islamic Azad University, Rasht, Iran ,
Abstract :
The direct three component modified Mannich reaction via condensation of aldehydes, 2-naphthol or 2,7-naphthalendiol and piperidine to generate Betti bases has been carried out over L-proline (20 mol%) with high efficiency under solvent-free conditions at 70°C. Also, the reaction of aromatic aldehyde and 4-hydroxycoumarin in the presence of L-proline (20 mol%) in the ethanol under reflux conditions, lead to biscoumarin derivatives.
