Title of article
Determination of Effect of Esfand (Peganumharmala) Seed Extract on Fear Behavior in Male Rats with varying Ages
Author/Authors
Ghorbani، Monireh نويسنده M.Sc. in Animal Physiology – Islamic Azad University – Damghan Branch , , Vaezi، Gholam-Hassan نويسنده Associate professor – Islamic Azad University – Damghan Branch , , Shajiee، Hooman نويسنده Assistant professor – Islamic Azad University – Damghan Branch ,
Issue Information
روزنامه با شماره پیاپی سال 2013
Pages
6
From page
46
To page
51
Abstract
The present study was formulated in order to determine effect of inhalation of Esfand seeds extract on fear
behavior in the rats with varying ages (i.e. 20-, 35-, 50-, and 20-35-50-day old). The extract was provided from
the Esfand collected from Damghan Desert. The rats were subjected to inhalation of the extract at 12 mg/kg.
Elevated-plus maze was adopted in order to assess fear in the rats. The results showed that inhalation of Esfand
seeds extract increased the time spent and the number of visits to closed arm and the area between closed arm
and neutral area in test rats as compared to control rats. This was considered as indicative of fear behavior. This
effect was attributed to the neurotransmitters harmaline and harmine in the extract.
Journal title
Journal of Applied Environmental and Biological Sciences
Serial Year
2013
Journal title
Journal of Applied Environmental and Biological Sciences
Record number
2037435
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