Author/Authors :
Momoi، نويسنده , , Yasuyuki and Okai، نويسنده , , Yoshiko and Watari، نويسنده , , Toshihiro and Goitsuka، نويسنده , , Ryo and Tsujimoto، نويسنده , , Hajime and Hasegawa، نويسنده , , Atsuhiko، نويسنده ,
Abstract :
A canine lymphoma cell line (CL-1) was established in culture from tumor cells found in the pleural fluid of a 7-year old female Japanese terrier with thymic form lymphoma. The CL-1 cells were positive for CD45 and MHC class II and negative for CD4, CD5, CD8, Thy-1 and B-cell specific antigen and surface immunoglobulin. The CL-1 cells had a rearranged T-cell receptor β-chain gene and a germ-line form immunoglobulin gene, indicating that the CL-1 cells represented a monoclonally expanded population of canine αβ T-cell lineage.
