Title of article :
Characterization of anti-feline CD8 monoclonal antibodies
Author/Authors :
Shimojima، نويسنده , , Masayuki and Pecoraro، نويسنده , , Marcelo R and Maeda، نويسنده , , Ken and Tohya، نويسنده , , Yukinobu and Miyazawa، نويسنده , , Takayuki and Mikami، نويسنده , , Takeshi، نويسنده ,
Abstract :
We generated three monoclonal antibodies (mAbs) (2D7, 10C7 and 12A3) reactive to the α-chain of feline CD8 (fCD8) molecule. Further we showed that reference anti-fCD8 mAbs, FT2, 3.357 and vpg9 recognize the β-chain, α-chain and αβ-complex epitope, respectively. Flow cytometric analysis using these mAbs suggested that fCD8α+β- cells were present in lymphocytes of spleen, but not significantly in those of thymus, lymph nodes and peripheral blood of normal kittens.
Keywords :
monoclonal antibody , lymphocyte , CD8 , CAT
Journal title :
Astroparticle Physics
