Author/Authors :
Ghaffari-Nejad، Alireza نويسنده Department of Psychiatry, Kerman Neuroscience Research Centre, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, IR Iran Ghaffari-Nejad, Alireza , Mashayekhi، Azadeh نويسنده Department of Psychiatry, Kerman University of Medical Sciences, Kerman, IR Iran Mashayekhi, Azadeh , Mazhari، Shahrzad نويسنده Kerman Neuroscience Research Center, Department of Psychiatry, Kerman University of Medical Sciences, Kerman, Iran Mazhari, Shahrzad , Ghayoumi، Alireza نويسنده Department of Traditional Medicine, Tehran University of Medical Sciences, Tehran, IR Iran Ghayoumi, Alireza
Abstract :
Background: Drug non adherence is one of the major problems in treatment of psychiatric patients which could increase the risk of relapse and re-hospitalization.
Objectives: The aim of this study is to determine factors associated with drug non adherence by patients with mood disorders after their discharge from hospital and assessment of relation between drug attitude and drug adherence.
Patients and Methods: In this cohort, prospective, and descriptive study, 150 patients with mood disorders (major depressive disorder, bipolar mood disorder) at the time of discharge were assessed. For each patient, demographic information form and Drug Attitude Inventory (DAI-10) [persian translation] was completed at the time of discharge. Then all of the patients were monitored monthly until 6 months through telephone. In every follow up DAI-10 and drug use inventory (which consists of causes of drug non adherence) were completed. Finally relation between different variables and patient drug attitude with drug adherence were assessed.
Results: From all studied variables such as demographic factors, diagnosis, treatment factors, and drug attitude, only drug attitude had a significant relation with drug adherence.
Conclusions: Patients’ attitude toward drugs has a major role in drug adherence.