DNA-modified Carbon Nanotubes for Self-assembling and Biosensing Applications

We have demonstrated that specific DNA sequences could be covalently immobilized onto acid-oxidized and plasma-activated carbon nanotubes. While various functional supramolecular structures could be prepared by self-assembling of the acid-oxidized carbon nanotubes attached with DNA chains of complementary sequences, the DNA-immobilized aligned carbon nanobues have been demonstrated to be significant for sensing complementary DNA and/or target DNA chains of specific sequences with a high sensitivity and selectivity.