A New Ti–15Zr–4Nb–4Ta alloy for medical applications

V ions exhibit cytotoxicity in a culture medium from concentrations of ≧0.2 mg/L. Ti, Zr, Nb and Ta are biocompatible elements. A new Ti–15Zr–4Nb–4Ta alloy for medical implants is being developed. Its microstructure, mechanical properties, corrosion resistance and corrosion fatigue properties in a physiological saline solution, biocompatibility with cultured cells, new bone tissue response through rat tibia implantation and surface modification are discussed. Medical applications will be also addressed.