Synthesis, characterization and drug delivery activity of poly(anthranilicacid) based triblock copolymer

The poly(tetrahydrofuran) (PTHF) grafted poly(caprolactone)-poly(anthranilicacid)-poly(caprolactone) (PCL-PAA-PCL) co-polymer system was synthesized by using a prepolymer under nitrogen atmosphere in the presence of a stannous octoate catalyst. The [M0/I0] was maintained at 100. The polymers at each stage was characterized by various analytical techniques like FTIR spectroscopy, NMR spectroscopy, UV–visible spectroscopy, fluorescence spectroscopy, cyclic voltammetry, DSC, TGA, conductivity, FESEM, solubility test, cytotoxicity and drug release study. The results obtained here in the present investigation are critically compared with the literature values.