Bioactivity study of glass-ceramics with various crystalline fractions obtained by controlled crystallization

Tests were performed “in vitro” in order to analyse the bioactivity of a glass-ceramic composition (soda–lime–silica glass). Samples of glass-ceramics with several crystallized fractions were controlled by crystallization. These glass-ceramics were exposed to a solution that simulates the fluid body obtained (SBF-K9) for 18 up to 200 h. The evolution of silica-gel layer, amorphous calcium phosphate and hydroxycarbonateapatite (HCA) formation was analysed using Fourier transform infrared spectroscopy (FTIR). All the glass-ceramics showed the formation of a well-developed HCA layer on its surface in less than 100 h of exposure time.