Comparative wettability study of polystyrene functionalized with different proteins

Protein adsorption plays a part in the interfacial interactions needed for improving implants biospecificity. In this study, we functionalize polystyrene, which is a biomaterial commonly used for vascular implants, by different adhesion proteins such as fibronectin, collagen, albumin, heparin and immunoglobulin G. Each surface layer is characterized by three techniques: the Wilhelmy technique, the sessile drop and the captive bubble methods. Each technique provides complementary information. Wetting measurements provide a comparative study between the physico-chemical states of different proteins.