Synthesis and characterization of a potential material as internal fixation of bone fracture

A new unsaturated poly (ester–amide) viz phthalic anhydride–maleic anhydride–hexane diamine–ethylene glycol–neopentylene glycol copolymer was prepared by melt polycondensation and characterized after sealed end with benzyl alcohol. Mechanical properties and degradation behavior of the cross-linked unsaturated poly (ester–amide) were measured. Moreover, the hydrolysis behavior of cross-linked unsaturated poly (ester–amide) in 1.0 mol/L NaOH standard solution at room temperature was also studied. At the same time, preliminary biocompatibility under mice skin was evaluated. All the preliminary results suggested that the copolymer might be a potential bone internal fixation material.